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What Is A Double Marker Test?

A Double Marker Test is a type of test that in mainly given to pregnant women to determine any chromosomal malformation in the foetus. This test also plays a vital role in the detection of any kind of neurological conditions in the foetus, such as down’s syndrome or Edward’s Syndrome. Chromosomal abnormalities in foetus can result in serious developmental deformities and lead to various health problems in the child post birth, but such abnormalities are extremely rare. The Double Marker Test is especially given to pregnant women above 35 years of age and those who have a family history of birth defects and history insulin – dependent type 1 diabetes.

Preparation Of Double Marker Test

The Double Marker Test is a simple blood test and does not require any preparations. However, the doctor must be intimidated about the medications being taken prior to taking the test.

Uses Of Double Marker Test

The varied uses of the Double Marker Test are as follows;

  • It helps in assessing whether the unborn baby is at risk for any mental disorder
  • It is used primarily for the detection of Down syndrome
  • Double Marker Test also helps to detect Trisomy 18, that results in mental retardation and severe birth defects
  • It also helps in the detection of Trisomy 21.T, which cause mental disorders, heart disorders and other health conditions affecting vital organs

Double Marker Test Procedure

A Double Marker Test is done with an ultra – sound test and is done with a blood sample. The Double Marker Test looks for two markers namely Free Beta hCG (human chorionic gonadotrophin) and PAPP – A (Pregnancy associated plasma protein A).

Free Beta hCG is a glycoprotein hormone produced by the placenta during pregnancy. It’s high level is indicative to a higher risk of Trisomy 18 and Down’s syndrome.

PAPP – A is a vital plasma protein. A low level of plasma protein is indicative of the risk of down syndrome.

The test readings are signified in terms of screen positive, high risk and screen negative.

Double Marker Test Normal Value

The Double Marker Test normal value of hCG in pregnant women is 25700-288000 mIU/ml for all age groups, while the Double Market test normal value for PAPP – A is 1 MoM (multiple of median) for the female gender across all age groups.

Double Marker Test Cost

The Double Marker Test Cost varies due to various factors like city, quality and availability of the test, since this test is available in only select cities. The average Double Market Test Cost usually averages on the higher side and is quite expensive. The Double Market Test Cost in Bangalore averages anywhere between 2,500 to 3,500 rupees. But, these prices are only indicative and actual prices could vary.

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