LDH Test in Pune
The lactate dehydrogenase (LDH) test looks for signs of damage to the body’s tissues.
LDH is an enzyme found in almost every cell of your body, including your blood, muscles, brain, kidneys, and pancreas.
Your doctor might order one for any number of reasons, such as:
- To measure whether you have tissue damage and, if so, how much
- To monitor severe infections or conditions like hemolytic or megaloblastic anemias, kidney disease, and liver disease
- To help evaluate certain cancers or your cancer treatment
Higher LDH levels in blood may be a sign of tissue damage or disease. Your blood LDH level can also let your doctor know if your disease is getting worse or whether your treatment is working.
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Frequently Asked Questions
People with lactate dehydrogenase-A deficiency experience fatigue, muscle pain, and cramps during exercise (exercise intolerance). In some people with lactate dehydrogenase-A deficiency, high-intensity exercise or other strenuous activity leads to the breakdown of muscle tissue (rhabdomyolysis).
LDH is found in many of the body’s tissues and organs, including the muscles, liver, heart, pancreas, kidneys, brain and blood cells. The LDH test is mainly used to help identify the location and severity of tissue damage in the body. It’s also sometimes used to monitor how far certain conditions have progressed.
The reference range of LDH is between 140-280 U/L. This means that diabetes has adverse effects through increasing the levels of LDH. This is in agreement with other studies that reported higher levels of LDH in diabetic patients compared with control group (10).
Normal value range is 105 to 333 international units per liter (IU/L). Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples.
It increases at 12 hours and peaks at 24-48 hours. A very high level thus indicates acute myocardial infarction. Greater than a 50 times increase in LDH-1 and LDH-2 indicates megaloblastic anemia.
High LDH levels
High levels of LDH indicate some form of tissue damage. High levels of more than one isoenzyme may indicate more than one cause of tissue damage. For example, a patient with pneumonia could also have a heart attack. Extremely high levels of LDH could indicate severe disease or multiple organ failure.
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